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The Research Unit

Project 4 - Müller lab

Medicinal chemistry of Gq proteins and their inhibitors: synthesis, computational 
calculations and (bio)analytical studies

Project 6 - Kostenis lab

Revisiting long-held tenets in GPCR and G protein signal transduction with macrocyclic inhibitors of heterotrimeric Gq/11 proteins and state-of-the-art genome editing


Project 8 - Pfeifer lab

Impact of Gq signaling in the brown adipose tissue


Project 9 - Fleischmann/Wenzel lab

Effects of direct pharmacological Gq protein modulation on lung and right heart remodeling

Project 10 - Tüting/Gaffal

Gq/11-mediated GPCR signaling in melanoma pathogenesis and therapy